Greenfield School offers a comprehensive athletic program for both Middle and Upper School students. Junior Varsity sports are offered to grades seven through ten and Varsity Sports are offered to grades seven through twelve.
The school is a member of the Coastal Plains Independent Conference (CPIC) and the North Carolina Independent Schools Athletic Association (NCISAA).
Other CPIC members include:
Greenfield has won 27 1A NCISAA State Championships and 30 1A NCISAA State Runner-Ups. Greenfield School has been awarded two Wells Fargo cups in 2003-2004 and 2009-2010 for the Best Overall Athletic Program in 1A.